Marguerite-D'Youville is a regional county municipality located in the Montérégie region of southwestern Quebec, Canada. The seat is in Verchères.
The RCM was formerly named Lajemmerais Regional County Municipality, after Christophe du Frost de Lajemmerais, the father of Marguerite d'Youville. On February 12, 2011, the name was changed to honour d'Youville directly.